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Gene: Becn1 (beclin 1, autophagy related) Mus musculus
Symbol: Becn1
Name: beclin 1, autophagy related
Description: Exhibits identical protein binding activity. Involved in several processes, including engulfment of apoptotic cell; negative regulation of cellular metabolic process; and vacuole organization. Localizes to several cellular components, including autophagosome; phosphatidylinositol 3-kinase complex, class III; and trans-Golgi network. Predicted to colocalize with mitochondrion. Is expressed in central nervous system; extraembryonic visceral endoderm; sensory organ; and spleen. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Machado-Joseph disease. Orthologous to human BECN1 (beclin 1); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; mitochondrial autophagy pathway; INTERACTS WITH (-)-citrinin; (S)-nicotine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4921513J16Rik; 5430417M23Rik; Atg6; Bcl-2-interacting protein beclin; beclin-1; coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; MGC6843
Homo sapiens (human) : BECN1 (beclin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Becn1 (beclin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Becn1 (beclin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BECN1 (beclin 1)
Canis lupus familiaris (dog) : BECN1 (beclin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Becn1 (beclin 1)
Sus scrofa (pig) : BECN1 (beclin 1)
Chlorocebus sabaeus (African green monkey) : BECN1 (beclin 1)
Heterocephalus glaber (naked mole-rat) : Becn1 (beclin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11101,285,952 - 101,302,286 (-)EnsemblGRCm38mm10GRCm38
GRCm3811101,288,258 - 101,302,286 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711101,149,581 - 101,163,581 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611102,067,439 - 102,081,397 (-)NCBImm8
MGSCv3611101,104,357 - 101,118,357 (-)NCBImm8
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Becn1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736173
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.