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Gene: Psmb8 (proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)) Mus musculus
Symbol: Psmb8
Name: proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
Description: Predicted to have endopeptidase activity. Involved in antigen processing and presentation and fat cell differentiation. Localizes to proteasome core complex and spermatoproteasome complex. Human ortholog(s) of this gene implicated in JMP syndrome. Is expressed in thymus primordium. Orthologous to human PSMB8 (proteasome 20S subunit beta 8); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: large multifunctional protease 7; Lmp-7; Lmp7; low molecular mass protein 7; macropain subunit C13; MC13 (LMP7); multicatalytic endopeptidase complex subunit C13; proteasome component C13; proteasome subunit beta type 8; proteasome subunit beta type-8; proteasome subunit beta-5i; proteasome subunit MC13; proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteosome beta 8 subunit
Homo sapiens (human) : PSMB8 (proteasome 20S subunit beta 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Psmb8 (proteasome 20S subunit beta 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psmb8 (proteasome 20S subunit beta 8)
Pan paniscus (bonobo/pygmy chimpanzee) : PSMB8 (proteasome 20S subunit beta 8)
Canis lupus familiaris (dog) : PSMB8 (proteasome 20S subunit beta 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psmb8 (proteasome 20S subunit beta 8)
Sus scrofa (pig) : PSMB8 (proteasome 20S subunit beta 8)
Chlorocebus sabaeus (African green monkey) : PSMB8 (proteasome 20S subunit beta 8)
Heterocephalus glaber (naked mole-rat) : Psmb8 (proteasome 20S subunit beta 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1734,197,721 - 34,201,454 (+)EnsemblGRCm38mm10GRCm38
GRCm381734,198,195 - 34,201,454 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,335,140 - 34,338,399 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,808,611 - 33,811,478 (+)NCBImm8
Celera1736,951,781 - 36,955,036 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Psmb8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736194
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.