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Gene: Macroh2a1 (macroH2A.1 histone) Mus musculus
Symbol: Macroh2a1
Name: macroH2A.1 histone
CRRD ID: 736206
Description: Exhibits nucleosomal DNA binding activity and promoter-specific chromatin binding activity. Involved in negative regulation of transcription of nucleolar large rRNA by RNA polymerase I; regulation of lipid metabolic process; and regulation of response to oxidative stress. Localizes to condensed chromosome and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human MACROH2A1 (macroH2A.1 histone).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: core histone macro-H2A.1; H2A histone family, member Y; H2A.y; H2A/y; H2af; H2AF12; H2AF12M; H2afy; histone macroH2A1; MACROH2; macroH2A1.2; mH2a; mH2a1
Homo sapiens (human) : MACROH2A1 (macroH2A.1 histone)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Macroh2a1 (macroH2A.1 histone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102008188 (core histone macro-H2A.1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100974858 (core histone macro-H2A.1)
Canis lupus familiaris (dog) : MACROH2A1 (macroH2A.1 histone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101971629 (core histone macro-H2A.1)
Sus scrofa (pig) : H2AFY (H2A histone family, member Y)
Chlorocebus sabaeus (African green monkey) : H2AFY (core histone macro-H2A.1)
Heterocephalus glaber (naked mole-rat) : LOC101706296 (core histone macro-H2A.1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,073,619 - 56,136,361 (-)EnsemblGRCm38mm10GRCm38
MGSCv371356,174,983 - 56,236,911 (-)NCBIGRCm37mm9NCBIm37
MGSCv361356,083,796 - 56,145,137 (-)NCBImm8
Celera1357,128,470 - 57,190,557 (-)NCBICelera
Cytogenetic Map13B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Macroh2a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736206
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.