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Gene: IL4 (interleukin 4) Homo sapiens
Symbol: IL4
Name: interleukin 4
Description: Predicted to have cytokine activity. Involved in several processes, including T-helper 2 cell cytokine production; positive regulation of macromolecule metabolic process; and regulation of cell migration. Predicted to localize to extracellular space. Implicated in several diseases, including autoimmune hypersensitivity disease (multiple); hepatitis B; hepatitis C; pancreatic cancer (multiple); and vasculitis (multiple). Biomarker of several diseases, including allergic rhinitis; alopecia universalis; anogenital venereal wart; autoimmune hypersensitivity disease (multiple); and liver disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B cell growth factor 1; B-cell stimulatory factor 1; B_cell stimulatory factor 1; BCGF-1; BCGF1; binetrakin; BSF-1; BSF1; IL-4; interleukin 4 variant 2; interleukin-4; lymphocyte stimulatory factor 1; MGC79402; pitrakinra
Mus musculus (house mouse) : Il4 (interleukin 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il4 (interleukin 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il4 (interleukin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : IL4 (interleukin 4)
Canis lupus familiaris (dog) : IL4 (interleukin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il4 (interleukin 4)
Sus scrofa (pig) : IL4 (interleukin 4)
Chlorocebus sabaeus (African green monkey) : IL4 (interleukin 4)
Heterocephalus glaber (naked mole-rat) : Il4 (interleukin 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl5132,673,986 - 132,682,678 (+)EnsemblGRCh38hg38GRCh38
GRCh385132,673,986 - 132,682,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375132,009,678 - 132,018,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,037,272 - 132,046,267 (+)NCBINCBI36hg18NCBI36
Build 345132,037,271 - 132,046,267NCBI
Celera5128,139,502 - 128,148,524 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,201,979 - 127,210,672 (+)NCBIHuRef
CHM1_15131,442,973 - 131,451,670 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences