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Gene: CD8B (CD8b molecule) Homo sapiens
Symbol: CD8B
Name: CD8b molecule
Description: Predicted to have MHC class I protein binding activity and coreceptor activity. Predicted to be involved in regulation of defense response to virus by virus and regulation of immune response. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cd8 antigen, beta chain; CD8 antigen, beta polypeptide 1 (p37); CD8B1; Leu2; Ly3; LYT3; MGC119115; P37; T lymphocyte surface glycoprotein beta chain; T-cell surface glycoprotein CD8 beta chain
Mus musculus (house mouse) : Cd8b1 (CD8 antigen, beta chain 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd8b (CD8b molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd8b (CD8b molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD8B (CD8b molecule)
Canis lupus familiaris (dog) : CD8B (CD8b molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd8b (CD8b molecule)
Sus scrofa (pig) : CD8B (CD8b molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl286,815,339 - 86,861,924 (-)Ensembl
GRCh38286,815,337 - 86,861,924 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37287,042,460 - 87,089,047 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36286,895,971 - 86,942,549 (-)NCBINCBI36hg18NCBI36
Build 34286,989,886 - 87,000,696NCBI
Celera286,870,194 - 86,880,209 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef286,928,738 - 86,973,684 (-)NCBIHuRef
CHM1_1286,972,492 - 87,019,072 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CD8B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736307
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.