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Gene: Ptprq (protein tyrosine phosphatase, receptor type, Q) Mus musculus
Symbol: Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Description: Predicted to have protein tyrosine phosphatase activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; hematopoietic progenitor cell differentiation; and vestibular receptor cell morphogenesis. Localizes to the stereocilium bundle. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Is expressed in cochlea; crista ampullaris; inner ear vestibular component; macula of utricle; and saccule. Orthologous to human PTPRQ (protein tyrosine phosphatase receptor type Q); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH 17beta-estradiol (ortholog); 2,2',4,4'-Tetrabromodiphenyl ether (ortholog); acrylamide (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: phosphatidylinositol phosphatase PTPRQ; phosphotidylinositol phosphatase PTPRQ; PTP-RQ; R-PTP-Q; receptor-type tyrosine-protein phosphatase Q
Homo sapiens (human) : PTPRQ (protein tyrosine phosphatase receptor type Q)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptprq (protein tyrosine phosphatase, receptor type, Q)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprq (protein tyrosine phosphatase receptor type Q)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Canis lupus familiaris (dog) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprq (protein tyrosine phosphatase receptor type Q)
Sus scrofa (pig) : PTPRQ (protein tyrosine phosphatase receptor type Q)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3810107,514,363 - 107,720,098 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710106,954,416 - 107,157,083 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610106,921,470 - 107,124,137 (-)NCBImm8
Celera10109,459,813 - 109,656,738 (-)NCBICelera
Cytogenetic Map10 D1NCBI
cM Map1055.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptprq
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736320
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.