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Gene: BTC (betacellulin) Homo sapiens
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Symbol: BTC
Name: betacellulin
Description: Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in epidermal growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to localize to the extracellular space. Implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Biomarker of insulinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: probetacellulin
Orthologs:
Mus musculus (house mouse) : Btc (betacellulin, epidermal growth factor family member)  MGI  Alliance
Rattus norvegicus (Norway rat) : Btc (betacellulin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Btc (betacellulin)
Pan paniscus (bonobo/pygmy chimpanzee) : BTC (betacellulin)
Canis lupus familiaris (dog) : BTC (betacellulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Btc (betacellulin)
Sus scrofa (pig) : BTC (betacellulin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38474,744,759 - 74,794,718 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37475,671,448 - 75,719,882 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,890,472 - 75,938,853 (-)NCBINCBI36hg18NCBI36
Build 34476,028,626 - 76,077,008NCBI
Celera472,966,514 - 73,015,096 (-)NCBI
Cytogenetic Map4q13.3NCBI
HuRef471,418,290 - 71,466,739 (-)NCBIHuRef
CHM1_1475,646,457 - 75,696,381 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on BTC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736353
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.