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Gene: Prkcz (protein kinase C, zeta) Mus musculus
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Symbol: Prkcz
Name: protein kinase C, zeta
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including neuron projection extension; positive regulation of T-helper 2 cell differentiation; and positive regulation of cytokine production. Localizes to several cellular components, including axon hillock; myelin sheath abaxonal region; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PRKCZ (protein kinase C zeta); PARTICIPATES IN protein kinase C (PKC) signaling pathway; adenosine signaling pathway; angiotensin II signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI098070; aPKCzeta; atypical protein kinase C; C80388; nPKC-zeta; Pkcz; protein kinase C zeta subspecies; protein kinase C zeta type; R74924; zetaPKC
Orthologs:
Homo sapiens (human) : PRKCZ (protein kinase C zeta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prkcz (protein kinase C, zeta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcz (protein kinase C zeta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCZ (protein kinase C zeta)
Canis lupus familiaris (dog) : PRKCZ (protein kinase C zeta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcz (protein kinase C zeta)
Sus scrofa (pig) : PRKCZ (protein kinase C zeta)
Chlorocebus sabaeus (African green monkey) : PRKCZ (protein kinase C zeta)
Heterocephalus glaber (naked mole-rat) : Prkcz (protein kinase C zeta)
more info ...
Related Pseudogenes: Prkcz2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl4155,260,129 - 155,361,361 (-)EnsemblGRCm38mm10GRCm38
GRCm384155,260,118 - 155,361,428 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374154,634,229 - 154,735,500 (-)NCBIGRCm37mm9NCBIm37
MGSCv364154,103,920 - 154,205,191 (-)NCBImm8
Celera4157,534,125 - 157,635,425 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Prkcz
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736362
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.