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Gene: Prkcz (protein kinase C, zeta) Mus musculus
Symbol: Prkcz
Name: protein kinase C, zeta
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including neuron projection extension; positive regulation of T-helper 2 cell differentiation; and positive regulation of cytokine production. Localizes to several cellular components, including axon hillock; myelin sheath abaxonal region; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PRKCZ (protein kinase C zeta); PARTICIPATES IN protein kinase C (PKC) signaling pathway; adenosine signaling pathway; angiotensin II signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI098070; aPKCzeta; atypical protein kinase C; C80388; nPKC-zeta; Pkcz; protein kinase C zeta subspecies; protein kinase C zeta type; R74924; zetaPKC
Homo sapiens (human) : PRKCZ (protein kinase C zeta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prkcz (protein kinase C, zeta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcz (protein kinase C zeta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCZ (protein kinase C zeta)
Canis lupus familiaris (dog) : PRKCZ (protein kinase C zeta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcz (protein kinase C zeta)
Sus scrofa (pig) : PRKCZ (protein kinase C zeta)
Chlorocebus sabaeus (African green monkey) : PRKCZ (protein kinase C zeta)
Heterocephalus glaber (naked mole-rat) : Prkcz (protein kinase C zeta)
more info ...
Related Pseudogenes: Prkcz2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4155,260,129 - 155,361,361 (-)EnsemblGRCm38mm10GRCm38
GRCm384155,260,118 - 155,361,428 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374154,634,229 - 154,735,500 (-)NCBIGRCm37mm9NCBIm37
MGSCv364154,103,920 - 154,205,191 (-)NCBImm8
Celera4157,534,125 - 157,635,425 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prkcz
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736362
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.