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Gene: Kcnj1 (potassium inwardly-rectifying channel, subfamily J, member 1) Mus musculus
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Symbol: Kcnj1
Name: potassium inwardly-rectifying channel, subfamily J, member 1
Description: Predicted to have several functions, including ATP-activated inward rectifier potassium channel activity; phosphatidylinositol-4,5-bisphosphate binding activity; and potassium ion binding activity. Involved in several processes, including regulation of G-protein activated inward rectifier potassium channel activity; renal sodium ion absorption; and tissue homeostasis. Predicted to localize to the plasma membrane. Used to study Bartter disease type 2. Human ortholog(s) of this gene implicated in Bartter disease type 2. Is expressed in heart and metanephros. Orthologous to human KCNJ1 (potassium inwardly rectifying channel subfamily J member 1); PARTICIPATES IN aldosterone signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectifier potassium channel 1; inward rectifier K(+) channel Kir1.1; inwardly rectifying potassium channel ROMK-2; Kir1.1; potassium channel, inwardly rectifying subfamily J member 1; ROMK; Romk2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl932,372,493 - 32,399,197 (+)EnsemblGRCm38mm10GRCm38
GRCm38932,372,418 - 32,399,197 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37932,180,003 - 32,206,782 (+)NCBIGRCm37mm9NCBIm37
MGSCv36932,143,550 - 32,148,762 (+)NCBImm8
Celera929,635,143 - 29,662,007 (+)NCBICelera
Cytogenetic Map9A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kcnj1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736363
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.