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Gene: SCN2B (sodium voltage-gated channel beta subunit 2) Homo sapiens
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Symbol: SCN2B
Name: sodium voltage-gated channel beta subunit 2
Description: Exhibits sodium channel regulator activity and voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Involved in several processes, including cardiac muscle cell action potential; regulation of atrial cardiac muscle cell membrane depolarization; and regulation of heart rate by cardiac conduction. Localizes to the voltage-gated sodium channel complex. Implicated in familial atrial fibrillation.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB14; neuronal voltage-gated sodium channel beta 2 subunit; sodium channel beta 2 subunit; sodium channel subunit beta-2; sodium channel, voltage gated, type II beta subunit; sodium channel, voltage-gated, type II, beta polypeptide; sodium channel, voltage-gated, type II, beta subunit
Orthologs:
Mus musculus (house mouse) : Scn2b (sodium channel, voltage-gated, type II, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scn2b (sodium voltage-gated channel beta subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn2b (sodium voltage-gated channel beta subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN2B (sodium voltage-gated channel beta subunit 2)
Canis lupus familiaris (dog) : SCN2B (sodium voltage-gated channel beta subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn2b (sodium voltage-gated channel beta subunit 2)
Sus scrofa (pig) : SCN2B (sodium voltage-gated channel beta subunit 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,162,806 - 118,176,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,033,519 - 118,047,337 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,538,729 - 117,552,546 (-)NCBINCBI36hg18NCBI36
Build 3411117,538,728 - 117,552,546NCBI
Celera11115,191,374 - 115,205,190 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11113,967,183 - 113,980,997 (-)NCBIHuRef
CHM1_111117,919,350 - 117,933,166 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SCN2B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736397
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.