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Gene: Nr4a2 (nuclear receptor subfamily 4, group A, member 2) Mus musculus
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Symbol: Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including cellular response to corticotropin-releasing hormone stimulus; dopamine biosynthetic process; and nervous system development. Localizes to the nucleus. Used to study Parkinson's disease and schizophrenia. Human ortholog(s) of this gene implicated in Parkinson's disease. Is expressed in several structures, including ear; genitourinary system; integumental system; limb; and nervous system. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2); INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HZF-3; NOT; nuclear receptor subfamily 4 group A member 2; nur related protein 1; NUR-related factor 1; Nurr1; orphan nuclear receptor NURR1; RNR-1; TINOR; TINUR
Orthologs:
Homo sapiens (human) : NR4A2 (nuclear receptor subfamily 4 group A member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr4a2 (nuclear receptor subfamily 4, group A, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr4a2 (nuclear receptor subfamily 4 group A member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A2 (nuclear receptor subfamily 4 group A member 2)
Canis lupus familiaris (dog) : NR4A2 (nuclear receptor subfamily 4 group A member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a2 (nuclear receptor subfamily 4 group A member 2)
Sus scrofa (pig) : NR4A2 (nuclear receptor subfamily 4 group A member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38257,106,830 - 57,124,003 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37256,959,637 - 56,976,414 (-)NCBIGRCm37mm9NCBIm37
MGSCv36256,923,542 - 56,930,641 (-)NCBImm8
Celera258,866,926 - 58,883,671 (-)NCBICelera
Cytogenetic Map2 C1.1NCBI
cM Map231.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr4a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736400
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.