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Gene: Ptprj (protein tyrosine phosphatase, receptor type, J) Mus musculus
Symbol: Ptprj
Name: protein tyrosine phosphatase, receptor type, J
CRRD ID: 736434
Description: Exhibits protein tyrosine phosphatase activity. Involved in several processes, including regulation of cell migration; regulation of protein phosphorylation; and regulation of signal transduction. Localizes to immunological synapse and ruffle membrane. Is expressed in midbrain; renal calyx; renal pelvis; and superior colliculus. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; somatostatin signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI450271; BET; By; Byp; CD148; colon tumor susceptibility 1; DEP-; DEP-1; HPTP beta-like tyrosine phosphatase; protein-tyrosine phosphatase eta; protein-tyrosine phosphatase receptor type J; Ptpb2; PTPbeta2; R-PTP-eta; R-PTP-J; receptor-type tyrosine-protein phosphatase eta; RP; RPTPJ; Scc; Scc-; Scc-1; Scc1; susceptibility to colon cancer 1
Homo sapiens (human) : PTPRJ (protein tyrosine phosphatase receptor type J)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptprj (protein tyrosine phosphatase, receptor type, J)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprj (protein tyrosine phosphatase receptor type J)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRJ (protein tyrosine phosphatase receptor type J)
Canis lupus familiaris (dog) : PTPRJ (protein tyrosine phosphatase receptor type J)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprj (protein tyrosine phosphatase receptor type J)
Sus scrofa (pig) : PTPRJ (protein tyrosine phosphatase receptor type J)
Chlorocebus sabaeus (African green monkey) : PTPRJ (protein tyrosine phosphatase receptor type J)
Heterocephalus glaber (naked mole-rat) : Ptprj (protein tyrosine phosphatase receptor type J)
more info ...
Related Pseudogenes: Gm13767   Gm13768   Gm18953  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39290,260,100 - 90,411,102 (-)NCBI
GRCm38290,429,756 - 90,580,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl290,429,754 - 90,580,647 (-)EnsemblGRCm38mm10GRCm38
MGSCv37290,269,913 - 90,420,804 (-)NCBIGRCm37mm9NCBIm37
MGSCv36290,233,731 - 90,381,407 (-)NCBImm8
Celera291,810,313 - 91,967,158 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptprj
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736434
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.