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Gene: CD244 (CD244 molecule) Homo sapiens
Symbol: CD244
Name: CD244 molecule
CRRD ID: 736436
Description: Exhibits MHC class I protein binding activity. Involved in natural killer cell activation involved in immune response; positive regulation of inositol phosphate biosynthetic process; and regulation of cytokine production. Localizes to external side of plasma membrane. Implicated in rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2B4; CD244 molecule, natural killer cell receptor 2B4; h2B4; NAIL; natural killer cell receptor 2B4; NK cell activation inducing ligand NAIL; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; non mhc restricted killing associated; signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4
Mus musculus (house mouse) : Cd244a (CD244 molecule A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd244 (CD244 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd244 (CD244 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD244 (CD244 molecule)
Canis lupus familiaris (dog) : CD244 (CD244 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd244 (CD244 molecule)
Sus scrofa (pig) : CD244 (CD244 molecule)
Chlorocebus sabaeus (African green monkey) : CD244 (CD244 molecule)
Heterocephalus glaber (naked mole-rat) : Cd244 (CD244 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1160,830,160 - 160,862,887 (-)EnsemblGRCh38hg38GRCh38
GRCh381160,830,160 - 160,862,892 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371160,799,950 - 160,832,692 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,066,574 - 159,099,269 (-)NCBINCBI36hg18NCBI36
Build 341157,613,023 - 157,645,718NCBI
Celera1133,868,617 - 133,900,871 (-)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,156,082 - 132,188,997 (-)NCBIHuRef
CHM1_11162,195,333 - 162,228,071 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CD244
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736436
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.