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Gene: MEN1 (menin 1) Homo sapiens
Symbol: MEN1
Name: menin 1
Description: Exhibits several functions, including DNA binding activity; R-SMAD binding activity; and protein N-terminus binding activity. Contributes to histone-lysine N-methyltransferase activity. Involved in several processes, including negative regulation of nitrogen compound metabolic process; osteoblast development; and positive regulation of transforming growth factor beta receptor signaling pathway. Localizes to cleavage furrow; cytosol; and nuclear lumen. Implicated in endocrine gland cancer (multiple); hyperparathyroidism; and multiple endocrine neoplasia type 1. Biomarker of pancreatic ductal carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: endocrine adenomatosis, multiple; MEAI; menin; multiple endocrine neoplasia 1; multiple endocrine neoplasia I; SCG2
Mus musculus (house mouse) : Men1 (multiple endocrine neoplasia 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Men1 (menin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Men1 (menin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MEN1 (menin 1)
Canis lupus familiaris (dog) : MEN1 (menin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Men1 (menin 1)
Sus scrofa (pig) : MEN1 (menin 1)
Chlorocebus sabaeus (African green monkey) : MEN1 (menin 1)
Heterocephalus glaber (naked mole-rat) : Men1 (menin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1164,803,510 - 64,811,294 (-)EnsemblGRCh38hg38GRCh38
GRCh381164,803,514 - 64,811,294 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371164,570,986 - 64,578,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,327,564 - 64,335,342 (-)NCBINCBI36hg18NCBI36
Build 341164,327,571 - 64,335,342NCBI
Celera1161,897,163 - 61,904,940 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,898,267 - 60,932,150 (-)NCBIHuRef
CHM1_11164,454,762 - 64,462,538 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers