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Gene: Men1 (multiple endocrine neoplasia 1) Mus musculus
Symbol: Men1
Name: multiple endocrine neoplasia 1
Description: Exhibits chromatin binding activity and sequence-specific DNA binding activity. Predicted to contribute to histone-lysine N-methyltransferase activity. Involved in several processes, including chromatin organization; positive regulation of macromolecule metabolic process; and regulation of osteoblast differentiation. Localizes to the cytoplasm and nuclear chromosome, telomeric region. Used to study growth hormone secreting pituitary adenoma; hyperparathyroidism; multiple endocrine neoplasia type 1; and prolactinoma. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); hyperparathyroidism; and multiple endocrine neoplasia type 1. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; gonad; and sensory organ. Orthologous to human MEN1 (menin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW045611; menin
Homo sapiens (human) : MEN1 (menin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Men1 (menin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Men1 (menin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MEN1 (menin 1)
Canis lupus familiaris (dog) : MEN1 (menin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Men1 (menin 1)
Sus scrofa (pig) : MEN1 (menin 1)
Chlorocebus sabaeus (green monkey) : MEN1 (menin 1)
Heterocephalus glaber (naked mole-rat) : Men1 (menin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl196,334,979 - 6,340,891 (+)Ensembl
GRCm38196,334,979 - 6,340,894 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,334,979 - 6,340,894 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,335,039 - 6,340,889 (+)NCBImm8
Celera196,207,959 - 6,213,874 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Men1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736444
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.