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Gene: Men1 (multiple endocrine neoplasia 1) Mus musculus
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Symbol: Men1
Name: multiple endocrine neoplasia 1
Description: Exhibits chromatin binding activity and sequence-specific DNA binding activity. Predicted to contribute to histone-lysine N-methyltransferase activity. Involved in several processes, including chromatin organization; positive regulation of macromolecule metabolic process; and regulation of osteoblast differentiation. Localizes to the cytoplasm and nuclear chromosome, telomeric region. Used to study growth hormone secreting pituitary adenoma; hyperparathyroidism; multiple endocrine neoplasia type 1; and prolactinoma. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); hyperparathyroidism; and multiple endocrine neoplasia type 1. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; gonad; and sensory organ. Orthologous to human MEN1 (menin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW045611; menin
Orthologs:
Homo sapiens (human) : MEN1 (menin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Men1 (menin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Men1 (menin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MEN1 (menin 1)
Canis lupus familiaris (dog) : MEN1 (menin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Men1 (menin 1)
Sus scrofa (pig) : MEN1 (menin 1)
Chlorocebus sabaeus (green monkey) : MEN1 (menin 1)
Heterocephalus glaber (naked mole-rat) : Men1 (menin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,334,979 - 6,340,891 (+)Ensembl
GRCm38196,334,979 - 6,340,894 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,334,979 - 6,340,894 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,335,039 - 6,340,889 (+)NCBImm8
Celera196,207,959 - 6,213,874 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Men1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736444
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.