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Gene: OGT (O-linked N-acetylglucosamine (GlcNAc) transferase) Homo sapiens
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Symbol: OGT
Name: O-linked N-acetylglucosamine (GlcNAc) transferase
Description: Exhibits phosphatidylinositol-3,4,5-trisphosphate binding activity; protein N-acetylglucosaminyltransferase activity; and protein O-GlcNAc transferase activity. Contributes to histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); and histone acetyltransferase activity (H4-K8 specific). Involved in several processes, including histone modification; regulation of cellular protein metabolic process; and regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including the cytosol; histone acetyltransferase complex; and protein N-acetylglucosaminyltransferase complex. Implicated in X-linked mental retardation 106. Biomarker of aortic valve stenosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ23071; HINCUT-1; HRNT1; MGC22921; MRX106; o linked n-acetylglucosamine transferase; O-GLCNAC; O-GlcNAc transferase p110 subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT1; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,533,104 - 71,575,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,752,912 - 70,795,747 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,669,658 - 70,712,465 (+)NCBINCBI36hg18NCBI36
Build 34X70,535,953 - 70,578,761NCBI
CeleraX71,105,953 - 71,148,788 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,568,037 - 64,610,949 (+)NCBIHuRef
CHM1_1X70,645,269 - 70,688,159 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on OGT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736466
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.