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Gene: OGT (O-linked N-acetylglucosamine (GlcNAc) transferase) Homo sapiens
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Symbol: OGT
Name: O-linked N-acetylglucosamine (GlcNAc) transferase
CRRD ID: 736466
Description: Exhibits phosphatidylinositol-3,4,5-trisphosphate binding activity; protein N-acetylglucosaminyltransferase activity; and protein O-GlcNAc transferase activity. Contributes to histone acetyltransferase activity (H4-K16 specific); histone acetyltransferase activity (H4-K5 specific); and histone acetyltransferase activity (H4-K8 specific). Involved in several processes, including histone modification; regulation of cellular protein metabolic process; and regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including cytosol; histone acetyltransferase complex; and protein N-acetylglucosaminyltransferase complex. Implicated in X-linked mental retardation 106. Biomarker of aortic valve stenosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ23071; HINCUT-1; HRNT1; MGC22921; MRX106; o linked n-acetylglucosamine transferase; O-GLCNAC; O-GlcNAc transferase p110 subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT1; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX71,533,104 - 71,575,892 (+)EnsemblGRCh38hg38GRCh38
GRCh38X71,533,104 - 71,575,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,752,912 - 70,795,747 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,669,658 - 70,712,465 (+)NCBINCBI36hg18NCBI36
Build 34X70,535,953 - 70,578,761NCBI
CeleraX71,105,953 - 71,148,788 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,568,037 - 64,610,949 (+)NCBIHuRef
CHM1_1X70,645,269 - 70,688,159 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on OGT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736466
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.