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Gene: TK1 (thymidine kinase 1) Homo sapiens
Symbol: TK1
Name: thymidine kinase 1
Description: Exhibits identical protein binding activity and zinc ion binding activity. Involved in protein homotetramerization. Predicted to localize to the cytosol. Biomarker of breast cancer; cervix carcinoma; and lung non-small cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cytosolic thymidine kinase; thymidine kinase 1 soluble isoform; thymidine kinase 1, soluble; thymidine kinase, cytosolic; thymidine kinase-1; TK2
Mus musculus (house mouse) : Tk1 (thymidine kinase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tk1 (thymidine kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tk1 (thymidine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TK1 (thymidine kinase 1)
Canis lupus familiaris (dog) : TK1 (thymidine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tk1 (thymidine kinase 1)
Sus scrofa (pig) : TK1 (thymidine kinase 1)
Chlorocebus sabaeus (green monkey) : TK1 (thymidine kinase 1)
Heterocephalus glaber (naked mole-rat) : Tk1 (thymidine kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1778,174,091 - 78,187,233 (-)Ensembl
GRCh381778,174,079 - 78,187,204 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371776,170,160 - 76,183,285 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361773,681,755 - 73,694,880 (-)NCBINCBI36hg18NCBI36
Build 341773,681,775 - 73,694,726NCBI
Celera1772,766,591 - 72,779,726 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1771,594,292 - 71,607,377 (-)NCBIHuRef
CHM1_11776,234,697 - 76,247,823 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736473
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.