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Gene: G6PD (glucose-6-phosphate dehydrogenase) Homo sapiens
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Symbol: G6PD
Name: glucose-6-phosphate dehydrogenase
CRRD ID: 736474
Description: Exhibits several functions, including glucose binding activity; glucose-6-phosphate dehydrogenase activity; and protein homodimerization activity. Involved in several processes, including erythrocyte maturation; negative regulation of protein glutathionylation; and pentose-phosphate shunt, oxidative branch. Localizes to several cellular components, including centriolar satellite; cytoplasmic side of plasma membrane; and cytosol. Implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Biomarker of type 1 diabetes mellitus and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G6PD1; glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase, G6PD
Orthologs:
Mus musculus (house mouse) : G6pdx (glucose-6-phosphate dehydrogenase X-linked)  MGI  Alliance
Rattus norvegicus (Norway rat) : G6pd (glucose-6-phosphate dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pd (glucose-6-phosphate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PD (glucose-6-phosphate dehydrogenase)
Canis lupus familiaris (dog) : G6PD (glucose-6-phosphate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pd (glucose-6-phosphate dehydrogenase)
Sus scrofa (pig) : G6PD (glucose-6-phosphate dehydrogenase)
Chlorocebus sabaeus (African green monkey) : G6PD (glucose-6-phosphate dehydrogenase)
Heterocephalus glaber (naked mole-rat) : G6pd (glucose-6-phosphate dehydrogenase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX154,531,391 - 154,547,572 (-)EnsemblGRCh38hg38GRCh38
GRCh38X154,531,390 - 154,547,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,759,606 - 153,775,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,412,800 - 153,428,981 (-)NCBINCBI36hg18NCBI36
Build 34X153,323,309 - 153,339,173NCBI
CeleraX153,920,654 - 153,936,836 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,336,102 - 142,352,295 (-)NCBIHuRef
CHM1_1X153,671,374 - 153,687,570 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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