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Gene: UNC5B (unc-5 netrin receptor B) Homo sapiens
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Symbol: UNC5B
Name: unc-5 netrin receptor B
Description: Predicted to have netrin receptor activity. Involved in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of neuron apoptotic process; and positive regulation of phosphatidylinositol 3-kinase signaling. Predicted to localize to the integral component of membrane; membrane raft; and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: netrin receptor UNC5B; p53-regulated receptor for death and life protein 1; p53RDL1; transmembrane receptor Unc5H2; unc-5 homolog 2; unc-5 homolog B; UNC5H2
Orthologs:
Mus musculus (house mouse) : Unc5b (unc-5 netrin receptor B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Unc5b (unc-5 netrin receptor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc5b (unc-5 netrin receptor B)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC5B (unc-5 netrin receptor B)
Canis lupus familiaris (dog) : UNC5B (unc-5 netrin receptor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc5b (unc-5 netrin receptor B)
Sus scrofa (pig) : UNC5B (unc-5 netrin receptor B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381071,212,535 - 71,302,879 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371072,972,292 - 73,062,635 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361072,642,353 - 72,729,722 (+)NCBINCBI36hg18NCBI36
Build 341072,642,354 - 72,729,714NCBI
Celera1066,254,788 - 66,343,547 (+)NCBI
Cytogenetic Map10q22.1NCBI
HuRef1066,966,129 - 67,056,670 (+)NCBIHuRef
CHM1_11073,254,992 - 73,345,299 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on UNC5B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736493
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.