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Gene: CHP1 (calcineurin like EF-hand protein 1) Homo sapiens
Symbol: CHP1
Name: calcineurin like EF-hand protein 1
Description: Exhibits calcium ion binding activity and calcium-dependent protein binding activity. Involved in several processes, including negative regulation of calcineurin-NFAT signaling cascade; negative regulation of protein import into nucleus; and positive regulation of sodium:proton antiporter activity. Localizes to the plasma membrane. Implicated in spastic ataxia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcineurin B homolog; calcineurin B homologous protein 1; calcineurin B-like protein; calcineurin homologous protein; calcineurin-like EF hand protein 1; calcineurin-like EF-hand protein 1; calcium binding protein P22; calcium-binding protein CHP; calcium-binding protein p22; CHP; EF-hand calcium-binding domain-containing protein p22; FLJ20350; p22; p24; Sid470p; SLC9A1 binding protein; SLC9A1BP; SPAX9
Mus musculus (house mouse) : Chp1 (calcineurin-like EF hand protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chp1 (calcineurin-like EF-hand protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chp1 (calcineurin like EF-hand protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CHP1 (calcineurin like EF-hand protein 1)
Canis lupus familiaris (dog) : CHP1 (calcineurin like EF-hand protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chp1 (calcineurin like EF-hand protein 1)
Sus scrofa (pig) : CHP1 (calcineurin like EF-hand protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1541,230,839 - 41,281,887 (+)Ensembl
GRCh381541,231,156 - 41,281,887 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371541,523,341 - 41,574,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361539,310,729 - 39,361,377 (+)NCBINCBI36hg18NCBI36
Build 341539,310,728 - 39,361,373NCBI
Celera1518,291,415 - 18,342,063 (+)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1518,371,799 - 18,422,604 (+)NCBIHuRef
CHM1_11541,641,426 - 41,692,297 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736499
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.