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Gene: SOD3 (superoxide dismutase 3) Homo sapiens
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Symbol: SOD3
Name: superoxide dismutase 3
Description: Predicted to have copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Localizes to the collagen-containing extracellular matrix. Implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Biomarker of intermediate coronary syndrome and myocardial infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EC-SOD; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC20077; superoxide dismutase 3, extracellular; testicular tissue protein Li 175
Orthologs:
Mus musculus (house mouse) : Sod3 (superoxide dismutase 3, extracellular)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sod3 (superoxide dismutase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod3 (superoxide dismutase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD3 (superoxide dismutase 3)
Canis lupus familiaris (dog) : SOD3 (superoxide dismutase 3)
Sus scrofa (pig) : SOD3 (superoxide dismutase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38424,795,478 - 24,800,845 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37424,797,085 - 24,802,467 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36424,406,183 - 24,411,565 (+)NCBINCBI36hg18NCBI36
Build 34424,472,323 - 24,478,733NCBI
Celera425,246,551 - 25,251,936 (+)NCBI
Cytogenetic Map4p15.2NCBI
HuRef424,139,594 - 24,144,972 (+)NCBIHuRef
CHM1_1424,796,442 - 24,801,824 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SOD3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736515
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.