Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: EPHX1 (epoxide hydrolase 1) Homo sapiens
Analyze
Symbol: EPHX1
Name: epoxide hydrolase 1
Description: Exhibits epoxide hydrolase activity. Involved in epoxide metabolic process. Predicted to localize to the endoplasmic reticulum membrane. Implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Biomarker of Alzheimer's disease and lung non-small cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EPHX; EPOX; epoxide hydratase; epoxide hydrolase 1 microsomal; epoxide hydrolase 1, microsomal (xenobiotic); HYL1; MEH
Orthologs:
Mus musculus (house mouse) : Ephx1 (epoxide hydrolase 1, microsomal)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ephx1 (epoxide hydrolase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephx1 (epoxide hydrolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHX1 (epoxide hydrolase 1)
Canis lupus familiaris (dog) : EPHX1 (epoxide hydrolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephx1 (epoxide hydrolase 1)
Sus scrofa (pig) : EPHX1 (epoxide hydrolase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381225,810,074 - 225,845,563 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371225,997,797 - 226,033,264 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361224,079,599 - 224,099,884 (+)NCBINCBI36hg18NCBI36
Build 341222,319,710 - 222,339,996NCBI
Celera1199,188,853 - 199,224,327 (+)NCBI
Cytogenetic Map1q42.12NCBI
HuRef1196,515,661 - 196,550,964 (+)NCBIHuRef
CHM1_11227,270,100 - 227,305,585 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on EPHX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736560
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.