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Gene: Adcy8 (adenylate cyclase 8) Mus musculus
Symbol: Adcy8
Name: adenylate cyclase 8
Description: Exhibits calcium- and calmodulin-responsive adenylate cyclase activity. Involved in several processes, including cellular chemical homeostasis; long-term memory; and regulation of synaptic plasticity. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and neuronal cell body membrane. Predicted to colocalize with actin cytoskeleton. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; respiratory system; and sensory organ. Orthologous to human ADCY8 (adenylate cyclase 8); PARTICIPATES IN endothelin signaling pathway; bile acid transport pathway; dilated cardiomyopathy pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; bisphenol A; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AC8; adenylate cyclase type 8; adenylate cyclase type VIII; adenylyl cyclase 8; ATP pyrophosphate-lyase 8; AW060868; ca(2+)/calmodulin-activated adenylyl cyclase
Homo sapiens (human) : ADCY8 (adenylate cyclase 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adcy8 (adenylate cyclase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy8 (adenylate cyclase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY8 (adenylate cyclase 8)
Canis lupus familiaris (dog) : ADCY8 (adenylate cyclase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy8 (adenylate cyclase 8)
Sus scrofa (pig) : ADCY8 (adenylate cyclase 8)
Chlorocebus sabaeus (African green monkey) : ADCY8 (adenylate cyclase 8)
Heterocephalus glaber (naked mole-rat) : Adcy8 (adenylate cyclase 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1564,697,084 - 64,922,296 (-)EnsemblGRCm38mm10GRCm38
GRCm381564,699,035 - 64,922,296 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371564,530,597 - 64,753,858 (-)NCBIGRCm37mm9NCBIm37
MGSCv361564,528,707 - 64,751,833 (-)NCBImm8
Celera1566,221,302 - 66,448,865 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1529.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adcy8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736586
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.