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Gene: Adcy8 (adenylate cyclase 8) Mus musculus
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Symbol: Adcy8
Name: adenylate cyclase 8
Description: Exhibits calcium- and calmodulin-responsive adenylate cyclase activity. Involved in several processes, including cellular chemical homeostasis; long-term memory; and regulation of synaptic plasticity. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and neuronal cell body membrane. Predicted to colocalize with actin cytoskeleton. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; respiratory system; and sensory organ. Orthologous to human ADCY8 (adenylate cyclase 8); PARTICIPATES IN endothelin signaling pathway; bile acid transport pathway; dilated cardiomyopathy pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; bisphenol A; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AC8; adenylate cyclase type 8; adenylate cyclase type VIII; adenylyl cyclase 8; ATP pyrophosphate-lyase 8; AW060868; ca(2+)/calmodulin-activated adenylyl cyclase
Orthologs:
Homo sapiens (human) : ADCY8 (adenylate cyclase 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adcy8 (adenylate cyclase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy8 (adenylate cyclase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY8 (adenylate cyclase 8)
Canis lupus familiaris (dog) : ADCY8 (adenylate cyclase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy8 (adenylate cyclase 8)
Sus scrofa (pig) : ADCY8 (adenylate cyclase 8)
Chlorocebus sabaeus (African green monkey) : ADCY8 (adenylate cyclase 8)
Heterocephalus glaber (naked mole-rat) : Adcy8 (adenylate cyclase 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1564,697,084 - 64,922,296 (-)EnsemblGRCm38mm10GRCm38
GRCm381564,699,035 - 64,922,296 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371564,530,597 - 64,753,858 (-)NCBIGRCm37mm9NCBIm37
MGSCv361564,528,707 - 64,751,833 (-)NCBImm8
Celera1566,221,302 - 66,448,865 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1529.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adcy8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736586
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.