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Gene: Sqle (squalene epoxidase) Mus musculus
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Symbol: Sqle
Name: squalene epoxidase
Description: Predicted to have FAD binding activity and squalene monooxygenase activity. Predicted to be involved in several processes, including lipid droplet formation; regulation of cell population proliferation; and sterol metabolic process. Predicted to localize to endoplasmic reticulum and integral component of membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human SQLE (squalene epoxidase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AI323792; SE; squalene monooxygenase
Orthologs:
Homo sapiens (human) : SQLE (squalene epoxidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sqle (squalene epoxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sqle (squalene epoxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : SQLE (squalene epoxidase)
Canis lupus familiaris (dog) : SQLE (squalene epoxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sqle (squalene epoxidase)
Sus scrofa (pig) : SQLE (squalene epoxidase)
Chlorocebus sabaeus (African green monkey) : SQLE (squalene epoxidase)
Heterocephalus glaber (naked mole-rat) : Sqle (squalene epoxidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1559,315,077 - 59,331,192 (+)EnsemblGRCm38mm10GRCm38
GRCm381559,315,092 - 59,331,193 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371559,146,647 - 59,162,748 (+)NCBIGRCm37mm9NCBIm37
MGSCv361559,144,773 - 59,160,874 (+)NCBImm8
Celera1560,845,733 - 60,861,834 (+)NCBICelera
Cytogenetic Map15D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sqle
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736676
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.