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Gene: SLC25A14 (solute carrier family 25 member 14) Homo sapiens
Symbol: SLC25A14
Name: solute carrier family 25 member 14
Description: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BMCP-1; BMCP1; brain mitochondrial carrier protein 1; MGC149543; mitochondrial uncoupling protein 5; solute carrier family 25 (mitochondrial carrier, brain), member 14; UCP 5; UCP5
Mus musculus (house mouse) : Slc25a14 (solute carrier family 25 (mitochondrial carrier, brain), member 14)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc25a14 (solute carrier family 25 member 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc25a14 (solute carrier family 25 member 14)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC25A14 (solute carrier family 25 member 14)
Canis lupus familiaris (dog) : SLC25A14 (solute carrier family 25 member 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc25a14 (solute carrier family 25 member 14)
Sus scrofa (pig) : SLC25A14 (solute carrier family 25 member 14)
more info ...
Related Pseudogenes: SLC25A14P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X130,339,888 - 130,373,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X129,472,689 - 129,507,335 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X129,301,728 - 129,335,016 (+)NCBINCBI36hg18NCBI36
Build 34X129,199,581 - 129,232,870NCBI
CeleraX129,860,544 - 129,893,817 (+)NCBI
Cytogenetic MapXq26.1NCBI
HuRefX118,868,742 - 118,901,636 (+)NCBIHuRef
CHM1_1X129,385,504 - 129,418,976 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC25A14
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736693
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.