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Gene: YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) Homo sapiens
Symbol: YWHAZ
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
CRRD ID: 736756
Description: Exhibits several functions, including enzyme binding activity; identical protein binding activity; and ion channel binding activity. Involved in several processes, including Golgi reassembly; establishment of Golgi localization; and regulation of ERK1 and ERK2 cascade. Localizes to glutamatergic synapse. Biomarker of hepatocellular carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 14-3-3 delta; 14-3-3 protein zeta/delta; 14-3-3 protein/cytosolic phospholipase A2; 14-3-3 zeta; 14-3-3-zeta; epididymis luminal protein 4; epididymis secretory protein Li 3; epididymis secretory protein Li 93; HEL-S-3; HEL-S-93; HEL4; KCIP-1; MGC111427; MGC126532; MGC138156; phospholipase A2; POPCHAS; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; YWHAD
Related Pseudogenes: LOC100422669   YWHAZP1   YWHAZP10   YWHAZP2   YWHAZP3   YWHAZP4   YWHAZP5   YWHAZP6   YWHAZP7   YWHAZP8   YWHAZP9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl8100,916,523 - 100,953,388 (-)EnsemblGRCh38hg38GRCh38
GRCh388100,916,523 - 100,954,068 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378101,930,804 - 101,965,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,000,090 - 102,034,745 (-)NCBINCBI36hg18NCBI36
Build 348102,000,089 - 102,033,447NCBI
Celera898,115,836 - 98,150,667 (-)NCBI
Cytogenetic Map8q22.3NCBI
HuRef897,128,746 - 97,163,575 (-)NCBIHuRef
CHM1_18101,971,677 - 102,006,519 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on YWHAZ
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736756
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.