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Gene: Atf2 (activating transcription factor 2) Mus musculus
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Symbol: Atf2
Name: activating transcription factor 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and sequence-specific DNA binding activity. Involved in several processes, including adipose tissue development; fat cell differentiation; and positive regulation of transforming growth factor beta2 production. Localizes to the membrane; nucleus; and site of double-strand break. Used to study meconium aspiration syndrome and osteochondrodysplasia. Is expressed in several structures, including central nervous system; early conceptus; reproductive system; retina; and urinary system. Orthologous to human ATF2 (activating transcription factor 2); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; influenza A pathway; INTERACTS WITH (-)-anisomycin; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Atf-2; cAMP response element-binding protein CRE-BP1; cAMP-dependent transcription factor ATF-2; CRE-BP; Creb2; cyclic AMP-dependent transcription factor ATF-2; D130078H02Rik; D18875; MGC105211; MGC105222; mXBP; Tg(Gzma-Klra1)7Wum
Orthologs:
Homo sapiens (human) : ATF2 (activating transcription factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atf2 (activating transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf2 (activating transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF2 (activating transcription factor 2)
Canis lupus familiaris (dog) : ATF2 (activating transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf2 (activating transcription factor 2)
Sus scrofa (pig) : ATF2 (activating transcription factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl273,816,509 - 73,892,639 (-)Ensembl
GRCm38273,816,509 - 73,892,677 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37273,654,578 - 73,730,685 (-)NCBIGRCm37mm9NCBIm37
MGSCv36273,617,360 - 73,693,467 (-)NCBImm8
Celera275,503,531 - 75,579,505 (-)NCBICelera
Cytogenetic Map2 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Atf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736761
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.