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Gene: Pemt (phosphatidylethanolamine N-methyltransferase) Mus musculus
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Symbol: Pemt
Name: phosphatidylethanolamine N-methyltransferase
Description: Exhibits S-adenosylmethionine-dependent methyltransferase activity. Involved in blastocyst hatching; positive regulation of cold-induced thermogenesis; and sphingomyelin biosynthetic process. Localizes to endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; early conceptus; liver; lung; and secondary oocyte. Orthologous to human PEMT (phosphatidylethanolamine N-methyltransferase); PARTICIPATES IN choline metabolic pathway; glycerophospholipid metabolic pathway; remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI255394; PEAMT; Pempt; Pempt2; PEMT2; phospholipid methyltransferase; PLMT
Orthologs:
Homo sapiens (human) : PEMT (phosphatidylethanolamine N-methyltransferase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pemt (phosphatidylethanolamine N-methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pemt (phosphatidylethanolamine N-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : PEMT (phosphatidylethanolamine N-methyltransferase)
Canis lupus familiaris (dog) : PEMT (phosphatidylethanolamine N-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pemt (phosphatidylethanolamine N-methyltransferase)
Sus scrofa (pig) : PEMT (phosphatidylethanolamine N-methyltransferase)
Chlorocebus sabaeus (African green monkey) : PEMT (phosphatidylethanolamine N-methyltransferase)
Heterocephalus glaber (naked mole-rat) : Pemt (phosphatidylethanolamine N-methyltransferase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1159,970,614 - 60,046,489 (-)EnsemblGRCm38mm10GRCm38
GRCm381159,970,614 - 60,046,561 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371159,784,119 - 59,850,341 (-)NCBIGRCm37mm9NCBIm37
MGSCv361159,786,812 - 59,853,034 (-)NCBImm8
MGSCv361160,507,197 - 60,573,128 (-)NCBImm8
Cytogenetic Map11B1.3NCBI
cM Map1137.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pemt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736786
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.