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Gene: TFPI2 (tissue factor pathway inhibitor 2) Homo sapiens
Symbol: TFPI2
Name: tissue factor pathway inhibitor 2
CRRD ID: 736798
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in blood coagulation; cellular response to fluid shear stress; and negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Implicated in acute myeloid leukemia and retinal degeneration.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ21164; placental protein 5; PP5; REF1; retinal pigment epithelium cell factor 1; TFPI-2
Mus musculus (house mouse) : Tfpi2 (tissue factor pathway inhibitor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tfpi2 (tissue factor pathway inhibitor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfpi2 (tissue factor pathway inhibitor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TFPI2 (tissue factor pathway inhibitor 2)
Canis lupus familiaris (dog) : TFPI2 (tissue factor pathway inhibitor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfpi2 (tissue factor pathway inhibitor 2)
Sus scrofa (pig) : TFPI2 (tissue factor pathway inhibitor 2)
Chlorocebus sabaeus (African green monkey) : TFPI2 (tissue factor pathway inhibitor 2)
Heterocephalus glaber (naked mole-rat) : Tfpi2 (tissue factor pathway inhibitor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl793,885,396 - 93,890,753 (-)EnsemblGRCh38hg38GRCh38
GRCh38793,885,396 - 93,890,753 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37793,514,709 - 93,520,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36793,353,678 - 93,358,001 (-)NCBINCBI36hg18NCBI36
Build 34793,160,395 - 93,164,716NCBI
Celera788,214,047 - 88,218,363 (-)NCBI
Cytogenetic Map7q21.3NCBI
HuRef788,122,436 - 88,128,017 (-)NCBIHuRef
CHM1_1793,444,941 - 93,450,535 (-)NCBICHM1_1
CRA_TCAGchr7v2792,843,873 - 92,849,467 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TFPI2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736798
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.