Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ATP2B2 (ATPase plasma membrane Ca2+ transporting 2) Homo sapiens
Symbol: ATP2B2
Name: ATPase plasma membrane Ca2+ transporting 2
CRRD ID: 736839
Description: Exhibits several functions, including ATP binding activity; PDZ domain binding activity; and calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in several processes, including calcium ion transport; regulation of cytosolic calcium ion concentration; and sensory perception of sound. Localizes to several cellular components, including GABA-ergic synapse; glutamatergic synapse; and plasma membrane. Implicated in autosomal recessive nonsyndromic deafness 12.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATPase, Ca++ transporting, plasma membrane 2; plasma membrane Ca(2+)-ATPase; plasma membrane Ca2+ pump 2; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 2; PMCA2; PMCA2a; PMCA2i
Mus musculus (house mouse) : Atp2b2 (ATPase, Ca++ transporting, plasma membrane 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Canis lupus familiaris (dog) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Sus scrofa (pig) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Chlorocebus sabaeus (African green monkey) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Heterocephalus glaber (naked mole-rat) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl310,324,023 - 10,708,007 (-)EnsemblGRCh38hg38GRCh38
GRCh38310,324,023 - 10,707,962 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37310,365,707 - 10,733,131 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36310,342,744 - 10,466,546 (-)NCBINCBI36hg18NCBI36
Build 34310,342,744 - 10,466,546NCBI
Celera310,301,512 - 10,482,740 (-)NCBI
Cytogenetic Map3p25.3NCBI
HuRef310,348,273 - 10,482,006 (-)NCBIHuRef
HuRef310,301,047 - 10,335,597 (-)NCBIHuRef
CHM1_1310,315,744 - 10,497,280 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ATP2B2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736839
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.