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Gene: ATP2B2 (ATPase plasma membrane Ca2+ transporting 2) Homo sapiens
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Symbol: ATP2B2
Name: ATPase plasma membrane Ca2+ transporting 2
Description: Exhibits several functions, including ATP binding activity; PDZ domain binding activity; and calcium transmembrane transporter activity, phosphorylative mechanism. Involved in several processes, including calcium ion transport; regulation of cytosolic calcium ion concentration; and sensory perception of sound. Localizes to several cellular components, including the GABA-ergic synapse; glutamatergic synapse; and plasma membrane. Implicated in autosomal recessive nonsyndromic deafness 12.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATPase, Ca++ transporting, plasma membrane 2; plasma membrane Ca(2+)-ATPase; plasma membrane Ca2+ pump 2; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 2; PMCA2; PMCA2a; PMCA2i
Orthologs:
Mus musculus (house mouse) : Atp2b2 (ATPase, Ca++ transporting, plasma membrane 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Canis lupus familiaris (dog) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Sus scrofa (pig) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38310,324,023 - 10,707,962 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37310,365,707 - 10,733,131 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36310,342,744 - 10,466,546 (-)NCBINCBI36hg18NCBI36
Build 34310,342,744 - 10,466,546NCBI
Celera310,301,512 - 10,482,740 (-)NCBI
Cytogenetic Map3p25.3NCBI
HuRef310,301,047 - 10,335,597 (-)NCBIHuRef
HuRef310,348,273 - 10,482,006 (-)NCBIHuRef
CHM1_1310,315,744 - 10,497,280 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ATP2B2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736839
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.