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Gene: Homer2 (homer scaffolding protein 2) Mus musculus
Symbol: Homer2
Name: homer scaffolding protein 2
Description: Exhibits GKAP/Homer scaffold activity and actin binding activity. Involved in several processes, including behavioral response to cocaine; calcium-mediated signaling using intracellular calcium source; and chemical homeostasis within a tissue. Localizes to several cellular components, including glutamatergic synapse; postsynaptic density; and stereocilium tip. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Is expressed in several structures, including central nervous system; genitourinary system; lung; nose; and spleen. Orthologous to human HOMER2 (homer scaffold protein 2); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9330120H11Rik; AW539445; CPD; cupidin; homer homolog 2; homer protein homolog 2; homer, neuronal immediate early gene, 2; homer-2; VASP/Ena-related gene up-regulated during seizure and LTP 2; Vesl-2
Homo sapiens (human) : HOMER2 (homer scaffold protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Homer2 (homer scaffold protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Homer2 (homer scaffold protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HOMER2 (homer scaffold protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Homer2 (homer scaffold protein 2)
Sus scrofa (pig) : HOMER2 (homer scaffold protein 2)
Chlorocebus sabaeus (African green monkey) : HOMER2 (homer scaffold protein 2)
Heterocephalus glaber (naked mole-rat) : Homer2 (homer scaffold protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl781,600,481 - 81,707,527 (-)EnsemblGRCm38mm10GRCm38
GRCm38781,600,481 - 81,706,925 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37788,745,367 - 88,851,811 (-)NCBIGRCm37mm9NCBIm37
MGSCv36781,483,228 - 81,580,639 (-)NCBImm8
Celera779,009,788 - 79,104,812 (-)NCBICelera
Cytogenetic Map7D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Homer2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736904
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-04-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.