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Gene: Homer2 (homer scaffolding protein 2) Mus musculus
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Symbol: Homer2
Name: homer scaffolding protein 2
Description: Exhibits GKAP/Homer scaffold activity and actin binding activity. Involved in several processes, including behavioral response to cocaine; calcium-mediated signaling using intracellular calcium source; and chemical homeostasis within a tissue. Localizes to several cellular components, including glutamatergic synapse; postsynaptic density; and stereocilium tip. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Is expressed in several structures, including central nervous system; genitourinary system; lung; nose; and spleen. Orthologous to human HOMER2 (homer scaffold protein 2); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9330120H11Rik; AW539445; CPD; cupidin; homer homolog 2; homer protein homolog 2; homer, neuronal immediate early gene, 2; homer-2; VASP/Ena-related gene up-regulated during seizure and LTP 2; Vesl-2
Orthologs:
Homo sapiens (human) : HOMER2 (homer scaffold protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Homer2 (homer scaffold protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Homer2 (homer scaffold protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HOMER2 (homer scaffold protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Homer2 (homer scaffold protein 2)
Sus scrofa (pig) : HOMER2 (homer scaffold protein 2)
Chlorocebus sabaeus (African green monkey) : HOMER2 (homer scaffold protein 2)
Heterocephalus glaber (naked mole-rat) : Homer2 (homer scaffold protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl781,600,481 - 81,707,527 (-)EnsemblGRCm38mm10GRCm38
GRCm38781,600,481 - 81,706,925 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37788,745,367 - 88,851,811 (-)NCBIGRCm37mm9NCBIm37
MGSCv36781,483,228 - 81,580,639 (-)NCBImm8
Celera779,009,788 - 79,104,812 (-)NCBICelera
Cytogenetic Map7D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Homer2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736904
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-04-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.