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Gene: HRG (histidine rich glycoprotein) Homo sapiens
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Symbol: HRG
Name: histidine rich glycoprotein
Description: Exhibits several functions, including anion binding activity; heme binding activity; and zinc ion binding activity. Involved in several processes, including negative regulation of lamellipodium assembly; negative regulation of vascular endothelial growth factor signaling pathway; and positive regulation of focal adhesion assembly. Localizes to the cell surface and extracellular region. Implicated in thrombophilia and thrombosis. Biomarker of pancreatic adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp779H1622; histidine-proline-rich glycoprotein; histidine-rich glycoprotein; HPRG; HRGP; THPH11
Orthologs:
Mus musculus (house mouse) : Hrg (histidine-rich glycoprotein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hrg (histidine-rich glycoprotein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hrg (histidine rich glycoprotein)
Pan paniscus (bonobo/pygmy chimpanzee) : HRG (histidine rich glycoprotein)
Canis lupus familiaris (dog) : HRG (histidine rich glycoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hrg (histidine rich glycoprotein)
Sus scrofa (pig) : HRG (histidine rich glycoprotein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,665,975 - 186,678,235 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373186,383,747 - 186,396,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,866,492 - 187,878,717 (+)NCBINCBI36hg18NCBI36
Build 343187,866,499 - 187,878,724NCBI
Celera3184,820,230 - 184,832,456 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,793,470 - 183,805,692 (+)NCBIHuRef
CHM1_13186,347,695 - 186,359,980 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HRG
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736906
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.