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Gene: RAP1B (RAP1B, member of RAS oncogene family) Homo sapiens
Symbol: RAP1B
Name: RAP1B, member of RAS oncogene family
Description: Exhibits GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including Rap protein signal transduction; cellular response to cAMP; and positive regulation of integrin activation. Localizes to the cell-cell junction; cytosol; and lipid droplet.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp586H0723; FLJ18601; GTP-binding protein smg p21B; K-REV; RAL1B; Ras family small GTP binding protein RAP1B; ras-related protein Rap-1b; RAS-related protein RAP1B; small GTP binding protein
Mus musculus (house mouse) : Rap1b (RAS related protein 1b)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rap1b (RAP1B, member of RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rap1b (RAP1B, member of RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAP1B (RAP1B, member of RAS oncogene family)
Canis lupus familiaris (dog) : RAP1B (RAP1B, member of RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rap1b (RAP1B, member of RAS oncogene family)
Sus scrofa (pig) : RAP1B (RAP1B, member of RAS oncogene family)
Chlorocebus sabaeus (African green monkey) : RAP1B (RAP1B, member of RAS oncogene family)
Heterocephalus glaber (naked mole-rat) : Rap1b (RAP1B, member of RAS oncogene family)
more info ...
Related Pseudogenes: RAP1BP1   RAP1BP2   RAP1BP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1268,610,855 - 68,671,901 (+)EnsemblGRCh38hg38GRCh38
GRCh381268,610,899 - 68,671,901 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371269,004,619 - 69,054,385 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361267,290,919 - 67,340,641 (+)NCBINCBI36hg18NCBI36
Build 341267,290,918 - 67,340,644NCBI
Celera1268,668,392 - 68,717,826 (+)NCBI
Cytogenetic Map12q15NCBI
HuRef1266,093,121 - 66,105,030 (+)NCBIHuRef
CHM1_11268,972,799 - 69,022,538 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RAP1B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736930
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.