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Gene: Syt1 (synaptotagmin I) Mus musculus
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Symbol: Syt1
Name: synaptotagmin I
Description: Exhibits several functions, including calcium ion sensor activity; calcium-dependent phospholipid binding activity; and syntaxin-1 binding activity. Involved in modulation of chemical synaptic transmission; neurotransmitter secretion; and regulation of dopamine secretion. Localizes to several cellular components, including the glutamatergic synapse; presynaptic membrane; and secretory vesicle. Predicted to colocalize with the SNARE complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Orthologous to human SYT1 (synaptotagmin 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 1,2-dichloroethane; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW124717; G630098F17Rik; p65; synaptotagmin 1; synaptotagmin-1; SytI
Orthologs:
Homo sapiens (human) : SYT1 (synaptotagmin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Syt1 (synaptotagmin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syt1 (synaptotagmin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SYT1 (synaptotagmin 1)
Canis lupus familiaris (dog) : SYT1 (synaptotagmin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syt1 (synaptotagmin 1)
Sus scrofa (pig) : SYT1 (synaptotagmin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3810108,497,650 - 109,010,980 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710107,935,305 - 108,447,675 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610107,902,359 - 108,414,729 (-)NCBImm8
Celera10110,438,514 - 110,956,520 (-)NCBICelera
Cytogenetic Map10 D1NCBI
cM Map1056.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Syt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736945
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.