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Gene: Vtn (vitronectin) Mus musculus
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Symbol: Vtn
Name: vitronectin
Description: Exhibits extracellular matrix binding activity. Involved in several processes, including cell-matrix adhesion; oligodendrocyte differentiation; and positive regulation of cell-substrate adhesion. Localizes to the extracellular matrix. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; metanephros; and retina. Orthologous to human VTN (vitronectin); PARTICIPATES IN forkhead class A signaling pathway; vascular endothelial growth factor signaling pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI256434; S-protein; serum-spreading factor; Vn
Orthologs:
Homo sapiens (human) : VTN (vitronectin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vtn (vitronectin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vtn (vitronectin)
Pan paniscus (bonobo/pygmy chimpanzee) : VTN (vitronectin)
Canis lupus familiaris (dog) : VTN (vitronectin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vtn (vitronectin)
Sus scrofa (pig) : VTN (vitronectin)
Chlorocebus sabaeus (green monkey) : VTN (vitronectin)
Heterocephalus glaber (naked mole-rat) : Vtn (vitronectin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1178,499,091 - 78,502,324 (+)Ensembl
GRCm381178,499,120 - 78,502,325 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,312,622 - 78,315,827 (+)NCBIGRCm37mm9NCBIm37
MGSCv361178,315,481 - 78,318,519 (+)NCBImm8
Celera1188,131,193 - 88,134,398 (+)NCBICelera
Cytogenetic Map11 B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Vtn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736956
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.