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Gene: Capn10 (calpain 10) Mus musculus
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Symbol: Capn10
Name: calpain 10
Description: Predicted to have SNARE binding activity; calcium-dependent cysteine-type endopeptidase activity; and cytoskeletal protein binding activity. Involved in several processes, including positive regulation of transport; positive regulation of type B pancreatic cell apoptotic process; and type B pancreatic cell apoptotic process. Predicted to localize to several cellular components, including cell cortex; cytosol; and mitochondrion. Is expressed in dorsal root ganglion and renal calyx. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; polycystic ovary syndrome; and type 2 diabetes mellitus. Orthologous to human CAPN10 (calpain 10); INTERACTS WITH (S)-nicotine; 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW049679; calcium-activated neutral proteinase 10; calpain 8; calpain-10; CANP 10; Capn8; mKIAA1845
Orthologs:
Homo sapiens (human) : CAPN10 (calpain 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Capn10 (calpain 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Capn10 (calpain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : CAPN10 (calpain 10)
Canis lupus familiaris (dog) : CAPN10 (calpain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Capn10 (calpain 10)
Sus scrofa (pig) : CAPN10 (calpain 10)
Chlorocebus sabaeus (African green monkey) : CAPN10 (calpain 10)
Heterocephalus glaber (naked mole-rat) : Capn10 (calpain 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl192,934,376 - 92,947,941 (+)EnsemblGRCm38mm10GRCm38
GRCm38192,934,408 - 92,947,948 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,830,985 - 94,844,525 (+)NCBIGRCm37mm9NCBIm37
MGSCv36194,764,814 - 94,778,354 (+)NCBImm8
Celera195,879,004 - 95,892,543 (+)NCBICelera
Cytogenetic Map1DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Capn10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736979
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.