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Gene: CSF1R (colony stimulating factor 1 receptor) Homo sapiens
Symbol: CSF1R
Name: colony stimulating factor 1 receptor
CRRD ID: 737004
Description: Exhibits cytokine binding activity and macrophage colony-stimulating factor receptor activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of macromolecule metabolic process; and protein phosphorylation. Localizes to nucleoplasm and plasma membrane. Implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and renal cell carcinoma. Biomarker of breast cancer; cervical squamous cell carcinoma; cervix uteri carcinoma in situ; prostate carcinoma in situ; and renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BANDDOS; C-FMS; CD115; CD115 antigen; CSF-1 receptor; CSF-1-R; CSF-1R; CSFR; FIM2; FMS; FMS proto-oncogene; HDLS; M-CSF-R; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; proto-oncogene c-Fms
Mus musculus (house mouse) : Csf1r (colony stimulating factor 1 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Csf1r (colony stimulating factor 1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf1r (colony stimulating factor 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF1R (colony stimulating factor 1 receptor)
Canis lupus familiaris (dog) : CSF1R (colony stimulating factor 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf1r (colony stimulating factor 1 receptor)
Sus scrofa (pig) : CSF1R (colony stimulating factor 1 receptor)
Chlorocebus sabaeus (African green monkey) : CSF1R (colony stimulating factor 1 receptor)
Heterocephalus glaber (naked mole-rat) : Csf1r (colony stimulating factor 1 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl5150,053,291 - 150,113,372 (-)EnsemblGRCh38hg38GRCh38
GRCh385150,053,295 - 150,113,365 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375149,432,854 - 149,492,935 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365149,413,051 - 149,473,128 (-)NCBINCBI36hg18NCBI36
Build 345149,413,050 - 149,473,128NCBI
Celera5145,514,237 - 145,574,309 (-)NCBI
Cytogenetic Map5q32NCBI
HuRef5144,580,804 - 144,640,914 (-)NCBIHuRef
CHM1_15148,865,545 - 148,925,516 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CSF1R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737004
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.