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Gene: ETS1 (ETS proto-oncogene 1, transcription factor) Homo sapiens
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Symbol: ETS1
Name: ETS proto-oncogene 1, transcription factor
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and identical protein binding activity. Involved in several processes, including PML body organization; positive regulation of blood vessel endothelial cell migration; and pri-miRNA transcription by RNA polymerase II. Localizes to the nucleoplasm. Implicated in type 1 diabetes mellitus. Biomarker of type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; c-ets-1; ets protein; ETS-1; EWSR2; FLJ10768; p54; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1
Orthologs:
Mus musculus (house mouse) : Ets1 (E26 avian leukemia oncogene 1, 5' domain)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ets1 (ETS proto-oncogene 1, transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ets1 (ETS proto-oncogene 1, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : ETS1 (ETS proto-oncogene 1, transcription factor)
Canis lupus familiaris (dog) : ETS1 (ETS proto-oncogene 1, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ets1 (ETS proto-oncogene 1, transcription factor)
Sus scrofa (pig) : ETS1 (ETS proto-oncogene 1, transcription factor)
Chlorocebus sabaeus (African green monkey) : ETS1 (ETS proto-oncogene 1, transcription factor)
Heterocephalus glaber (naked mole-rat) : Ets1 (ETS proto-oncogene 1, transcription factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11128,458,761 - 128,587,558 (-)EnsemblGRCh38hg38GRCh38
GRCh3811128,458,761 - 128,587,593 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711128,328,656 - 128,457,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611127,833,870 - 127,897,371 (-)NCBINCBI36hg18NCBI36
Build 3411127,833,871 - 127,897,371NCBI
Celera11125,494,962 - 125,623,626 (-)NCBI
Cytogenetic Map11q24.3NCBI
HuRef11124,277,062 - 124,405,816 (-)NCBIHuRef
CHM1_111128,214,474 - 128,343,214 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ETS1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737031
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.