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Gene: CD44 (CD44 molecule (Indian blood group)) Homo sapiens
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Symbol: CD44
Name: CD44 molecule (Indian blood group)
CRRD ID: 737036
Description: Exhibits hyaluronic acid binding activity. Contributes to cytokine receptor activity. Involved in several processes, including negative regulation of signal transduction by p53 class mediator; positive regulation of cell-cell adhesion; and positive regulation of phosphorylation. Localizes to several cellular components, including apical plasma membrane; lamellipodium membrane; and macrophage migration inhibitory factor receptor complex. Implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Biomarker of Krukenberg carcinoma; invasive ductal carcinoma; leiomyomatosis; lung adenocarcinoma; and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD44 antigen; CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronate receptor; IN; Indian blood group antigen; LHR; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH-I; Pgp1; phagocytic glycoprotein 1; soluble CD44
Orthologs:
Mus musculus (house mouse) : Cd44 (CD44 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd44 (CD44 molecule (Indian blood group))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd44 (CD44 molecule (Indian blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : CD44 (CD44 molecule (Indian blood group))
Canis lupus familiaris (dog) : CD44 (CD44 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd44 (CD44 molecule (Indian blood group))
Sus scrofa (pig) : CD44 (CD44 molecule)
Chlorocebus sabaeus (African green monkey) : CD44 (CD44 molecule (Indian blood group))
Heterocephalus glaber (naked mole-rat) : Cd44 (CD44 molecule (Indian blood group))
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1135,138,882 - 35,232,402 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1135,138,870 - 35,232,402 (+)EnsemblGRCh38hg38GRCh38
GRCh381135,139,168 - 35,232,402 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371135,160,417 - 35,253,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361135,116,993 - 35,210,525 (+)NCBINCBI36hg18NCBI36
Build 341135,116,992 - 35,210,524NCBI
Celera1135,307,730 - 35,401,272 (+)NCBI
Cytogenetic Map11p13NCBI
HuRef1134,858,894 - 34,952,423 (+)NCBIHuRef
CHM1_11135,158,655 - 35,252,358 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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