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Gene: CD80 (CD80 molecule) Homo sapiens
Symbol: CD80
Name: CD80 molecule
Description: Predicted to have virus receptor activity. Involved in positive regulation of peptidyl-tyrosine phosphorylation. Localizes to protein complex involved in cell adhesion. Implicated in type 1 diabetes mellitus. Biomarker of chronic obstructive pulmonary disease; demyelinating disease; relapsing-remitting multiple sclerosis; rheumatoid arthritis; and systemic lupus erythematosus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activation B7-1 antigen; B-lymphocyte activation antigen B7; B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; cd80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
Mus musculus (house mouse) : Cd80 (CD80 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd80 (Cd80 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd80 (CD80 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD80 (CD80 molecule)
Canis lupus familiaris (dog) : CD80 (CD80 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd80 (CD80 molecule)
Sus scrofa (pig) : CD80 (CD80 molecule)
Chlorocebus sabaeus (African green monkey) : CD80 (CD80 molecule)
Heterocephalus glaber (naked mole-rat) : Cd80 (CD80 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl3119,524,293 - 119,559,614 (-)EnsemblGRCh38hg38GRCh38
GRCh383119,524,293 - 119,559,614 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373119,243,140 - 119,278,481 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,725,830 - 120,761,171 (-)NCBINCBI36hg18NCBI36
Build 343120,725,831 - 120,761,139NCBI
Celera3117,651,693 - 117,687,039 (-)NCBI
Cytogenetic Map3q13.33NCBI
HuRef3116,618,830 - 116,654,199 (-)NCBIHuRef
CHM1_13119,206,623 - 119,241,981 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CD80
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737082
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.