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Gene: Kitl (kit ligand) Mus musculus
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Symbol: Kitl
Name: kit ligand
Description: Exhibits cytokine activity and stem cell factor receptor binding activity. Involved in several processes, including ectopic germ cell programmed cell death; positive regulation of hemopoiesis; and positive regulation of protein phosphorylation. Localizes to the extracellular space; integral component of membrane; and plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human KITLG (KIT ligand); INTERACTS WITH 1,1-dichloroethene; 1-chloro-2,4-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: blz; C-kit ligand; Clo; cloud gray; Con; contrasted; Gb; grizzle-belly; hematopoietic growth factor KL; Kitlg; mast cell growth factor; Mgf; SCF; SF; Sl; SLF; Steel; Steel factor; stem cell factor
Orthologs:
Homo sapiens (human) : KITLG (KIT ligand)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kitlg (KIT ligand)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kitlg (KIT ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : KITLG (KIT ligand)
Canis lupus familiaris (dog) : KITLG (KIT ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kitlg (KIT ligand)
Sus scrofa (pig) : KITLG (KIT ligand)
Chlorocebus sabaeus (African green monkey) : KITLG (KIT ligand)
Heterocephalus glaber (naked mole-rat) : Kitlg (KIT ligand)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl10100,015,630 - 100,100,416 (+)Ensembl
GRCm3810100,015,615 - 100,100,416 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371099,478,458 - 99,563,046 (+)NCBIGRCm37mm9NCBIm37
MGSCv361099,445,512 - 99,530,100 (+)NCBImm8
Celera10101,983,926 - 102,068,221 (+)NCBICelera
Cytogenetic Map10 D1NCBI
cM Map1051.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kitl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737119
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.