Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LIPE (lipase E, hormone sensitive type) Homo sapiens
Analyze
Symbol: LIPE
Name: lipase E, hormone sensitive type
Description: Predicted to have carboxylic ester hydrolase activity; protein kinase binding activity; and serine hydrolase activity. Predicted to be involved in lipid catabolic process. Localizes to the cytosol. Implicated in familial partial lipodystrophy type 6 and hypertension. Biomarker of arteriosclerosis and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AOMS4; FPLD6; hormone-sensitive lipase; hormone-sensitive lipase testicular isoform; HSL; LHS; lipase, hormone sensitive; lipase, hormone-sensitive
Orthologs:
Mus musculus (house mouse) : Lipe (lipase, hormone sensitive)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lipe (lipase E, hormone sensitive type)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lipe (lipase E, hormone sensitive type)
Pan paniscus (bonobo/pygmy chimpanzee) : LIPE (lipase E, hormone sensitive type)
Canis lupus familiaris (dog) : LIPE (lipase E, hormone sensitive type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lipe (lipase E, hormone sensitive type)
Sus scrofa (pig) : LIPE (lipase E, hormone sensitive type)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,401,512 - 42,427,421 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,905,664 - 42,931,578 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,597,506 - 47,623,418 (-)NCBINCBI36hg18NCBI36
Build 341947,597,505 - 47,623,418NCBI
Celera1939,706,455 - 39,732,367 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,335,797 - 39,361,703 (-)NCBIHuRef
CHM1_11942,907,309 - 42,933,231 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LIPE
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737132
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.