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Gene: LIPE (lipase E, hormone sensitive type) Homo sapiens
Symbol: LIPE
Name: lipase E, hormone sensitive type
Description: Predicted to have carboxylic ester hydrolase activity; protein kinase binding activity; and serine hydrolase activity. Predicted to be involved in lipid catabolic process. Localizes to the cytosol. Implicated in familial partial lipodystrophy type 6 and hypertension. Biomarker of arteriosclerosis and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AOMS4; FPLD6; hormone-sensitive lipase; hormone-sensitive lipase testicular isoform; HSL; LHS; lipase, hormone sensitive; lipase, hormone-sensitive
Mus musculus (house mouse) : Lipe (lipase, hormone sensitive)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lipe (lipase E, hormone sensitive type)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lipe (lipase E, hormone sensitive type)
Pan paniscus (bonobo/pygmy chimpanzee) : LIPE (lipase E, hormone sensitive type)
Canis lupus familiaris (dog) : LIPE (lipase E, hormone sensitive type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lipe (lipase E, hormone sensitive type)
Sus scrofa (pig) : LIPE (lipase E, hormone sensitive type)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381942,401,512 - 42,427,421 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,905,664 - 42,931,578 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,597,506 - 47,623,418 (-)NCBINCBI36hg18NCBI36
Build 341947,597,505 - 47,623,418NCBI
Celera1939,706,455 - 39,732,367 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,335,797 - 39,361,703 (-)NCBIHuRef
CHM1_11942,907,309 - 42,933,231 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LIPE
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737132
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.