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Gene: GATA4 (GATA binding protein 4) Homo sapiens
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Symbol: GATA4
Name: GATA binding protein 4
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and co-SMAD binding activity. Contributes to DNA-binding transcription factor activity. Involved in several processes, including heart development; intestinal epithelial cell differentiation; and male gonad development. Localizes to the RNA polymerase II transcription factor complex and nuclear body. Implicated in congenital heart disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ASD2; GATA-binding factor 4; GATA-binding protein 4; MGC126629; TACHD; TOF; transcription factor GATA-4; VSD1
Orthologs:
Mus musculus (house mouse) : Gata4 (GATA binding protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gata4 (GATA binding protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gata4 (GATA binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GATA4 (GATA binding protein 4)
Canis lupus familiaris (dog) : GATA4 (GATA binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata4 (GATA binding protein 4)
Sus scrofa (pig) : GATA4 (GATA binding protein 4)
Chlorocebus sabaeus (green monkey) : GATA4 (GATA binding protein 4)
Heterocephalus glaber (naked mole-rat) : Gata4 (GATA binding protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl811,676,959 - 11,760,002 (+)Ensembl
GRCh38811,676,931 - 11,760,002 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37811,534,433 - 11,617,510 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36811,599,162 - 11,654,918 (+)NCBINCBI36hg18NCBI36
Build 34811,599,161 - 11,654,918NCBI
Celera810,690,994 - 10,746,848 (+)NCBI
Cytogenetic Map8p23.1NCBI
HuRef810,492,698 - 10,548,485 (+)NCBIHuRef
CHM1_1811,599,955 - 11,683,007 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GATA4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737140
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.