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Gene: MYH6 (myosin heavy chain 6) Homo sapiens
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Symbol: MYH6
Name: myosin heavy chain 6
Description: Exhibits actin-dependent ATPase activity; microfilament motor activity; and protein kinase binding activity. Involved in several processes, including heart development; muscle filament sliding; and regulation of heart contraction. Predicted to localize to the myofibril. Implicated in atrial heart septal defect (multiple); heart conduction disease (multiple); and intrinsic cardiomyopathy (multiple). Biomarker of congestive heart failure.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha myosin heavy chain; alpha-MHC; alpha-myosin heavy chain; ASD3; cardiomyopathy, hypertrophic 1; CMD1EE; CMH14; MYHC; myHC-alpha; MYHCA; myosin 6; myosin heavy chain, cardiac muscle alpha isoform; myosin heavy chain, polypeptide 6; myosin, heavy chain 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin-6; SSS3
Orthologs:
Mus musculus (house mouse) : Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Myh6 (myosin heavy chain 6)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MYH6 (myosin heavy chain 6)
Canis lupus familiaris (dog) : MYH6 (myosin heavy chain 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1423,381,982 - 23,408,273 (-)Ensembl
GRCh381423,381,990 - 23,408,277 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371423,849,942 - 23,878,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,921,039 - 22,947,322 (-)NCBINCBI36hg18NCBI36
Build 341422,921,037 - 22,947,324NCBI
Celera143,713,910 - 3,740,182 (-)NCBI
Cytogenetic Map14q11.2NCBI
HuRef143,967,617 - 3,993,925 (-)NCBIHuRef
CHM1_11423,849,871 - 23,876,158 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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RNA-SEQ Expression

Sequence

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