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Gene: IGF2 (insulin like growth factor 2) Homo sapiens
Symbol: IGF2
Name: insulin like growth factor 2
Description: Exhibits signaling receptor binding activity. Involved in positive regulation of activated T cell proliferation; positive regulation of mitotic nuclear division; and positive regulation of signal transduction. Predicted to localize to the extracellular region and platelet alpha granule lumen. Implicated in choriocarcinoma; hepatocellular carcinoma; and rheumatoid arthritis. Biomarker of several diseases, including Lewy body dementia; acquired immunodeficiency syndrome; arthritis (multiple); inflammatory bowel disease (multiple); and neurodegenerative disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C11orf43; FLJ22066; FLJ44734; GRDF; IGF-II; INSIGF; insulin-like growth factor 2 (somatomedin A); insulin-like growth factor II; insulin-like growth factor type 2; PP9974; preptin; putative insulin-like growth factor II associated protein; somatomedin A; somatomedin-A; T3M-11-derived growth factor
Mus musculus (house mouse) : Igf2 (insulin-like growth factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igf2 (insulin-like growth factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2 (insulin like growth factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2 (insulin like growth factor 2)
Canis lupus familiaris (dog) : IGF2 (insulin like growth factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2 (insulin like growth factor 2)
Sus scrofa (pig) : IGF2 (insulin like growth factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38112,129,112 - 2,149,603 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,150,346 - 2,179,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,106,923 - 2,127,409 (-)NCBINCBI36hg18NCBI36
Build 34112,110,531 - 2,116,578NCBI
Celera112,186,838 - 2,207,338 (-)NCBI
Cytogenetic Map11p15.5NCBI
HuRef111,940,869 - 1,961,095 (-)NCBIHuRef
CHM1_1112,148,968 - 2,169,786 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IGF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737149
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.