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Gene: Agtr1a (angiotensin II receptor, type 1a) Mus musculus
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Description: Exhibits angiotensin type I receptor activity. Involved in several processes, including circulatory system development; negative regulation of smooth muscle cell apoptotic process; and regulation of blood pressure. Localizes to the endosome and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); cerebrovascular disease (multiple); chronic kidney disease; and sarcoidosis. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; submandibular gland; and trophectoderm. Orthologous to human AGTR1 (angiotensin II receptor type 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (R)-lipoic acid; 1,1-dichloroethene; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810074K20Rik; AG2S; Agt1ar; Agtr-1a; Agtr1; AI551199; angiotensin II type-1A receptor; angiotensin receptor 1; angiotensin receptor 1a; Angtr-1a; AT1; AT1a; AT2R1; AT2R1A; MGC37610; type-1A angiotensin II receptor
Homo sapiens (human) : AGTR1 (angiotensin II receptor type 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Agtr1a (angiotensin II receptor, type 1a)  Alliance
Sus scrofa (pig) : AGTR1 (angiotensin II receptor type 1)
Chlorocebus sabaeus (African green monkey) : AGTR1 (angiotensin II receptor type 1)
Heterocephalus glaber (naked mole-rat) : Agtr1 (angiotensin II receptor type 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1330,336,441 - 30,382,867 (+)Ensembl
GRCm381330,336,356 - 30,382,867 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371330,428,225 - 30,474,736 (+)NCBIGRCm37mm9NCBIm37
MGSCv361330,343,922 - 30,390,332 (+)NCBImm8
Celera1330,550,710 - 30,597,281 (+)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Protein Structures

Additional Information

External Database Links
More on Agtr1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737190
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.