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Gene: Cyp17a1 (cytochrome P450, family 17, subfamily a, polypeptide 1) Mus musculus
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
CRRD ID: 737222
Description: Exhibits steroid 17-alpha-monooxygenase activity. Involved in glucocorticoid biosynthetic process. Localizes to axon and neuronal cell body. Is expressed in several structures, including adrenal gland; gut; nervous system; reproductive system; and retina layer. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; congenital adrenal hyperplasia; gallbladder cancer; osteoporosis; and prostate cancer. Orthologous to human CYP17A1 (cytochrome P450 family 17 subfamily A member 1); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 17-alpha-hydroxyprogesterone aldolase; Cyp1; Cyp17; CYPXVII; cytochrome P450 17A1; cytochrome P450, 17; cytochrome P450, 17a1; cytochrome P450-C17; cytochrome P450c17; p450c1; p450c17; steroid 17-alpha hydroxylase; steroid 17-alpha-hydroxylase/17,20 lyase; steroid 17-alpha-monooxygenase
Homo sapiens (human) : CYP17A1 (cytochrome P450 family 17 subfamily A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyp17a1 (cytochrome P450, family 17, subfamily a, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102011010 (steroid 17-alpha-hydroxylase/17,20 lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : CYP17A1 (cytochrome P450 family 17 subfamily A member 1)
Canis lupus familiaris (dog) : CYP17A1 (cytochrome P450 family 17 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101970767 (steroid 17-alpha-hydroxylase/17,20 lyase)
Sus scrofa (pig) : CYP17A1 (cytochrome P450 17A1)
Chlorocebus sabaeus (African green monkey) : CYP17A1 (cytochrome P450 family 17 subfamily A member 1)
Heterocephalus glaber (naked mole-rat) : LOC101726496 (steroid 17-alpha-hydroxylase/17,20 lyase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1946,667,165 - 46,673,172 (-)EnsemblGRCm38mm10GRCm38
GRCm381946,667,165 - 46,673,000 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371946,741,655 - 46,747,490 (-)NCBIGRCm37mm9NCBIm37
MGSCv361946,720,491 - 46,726,285 (-)NCBImm8
Celera1947,437,171 - 47,443,006 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cyp17a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737222
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.