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Gene: DDX1 (DEAD-box helicase 1) Homo sapiens
Symbol: DDX1
Name: DEAD-box helicase 1
Description: Exhibits several functions, including DNA/RNA helicase activity; poly(A) binding activity; and transcription coregulator activity. Involved in several processes, including DNA duplex unwinding; nucleic acid metabolic process; and protein localization to cytoplasmic stress granule. Localizes to several cellular components, including the cleavage body; cytoplasmic stress granule; and tRNA-splicing ligase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent RNA helicase DDX1; DBP-RB; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD box polypeptide 1; DEAD box protein 1; DEAD box protein retinoblastoma; DEAD box-1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1; DEAD/H-box helicase 1; UKVH5d
Mus musculus (house mouse) : Ddx1 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ddx1 (DEAD-box helicase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx1 (DEAD-box helicase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX1 (DEAD-box helicase 1)
Canis lupus familiaris (dog) : DDX1 (DEAD-box helicase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx1 (DEAD-box helicase 1)
Sus scrofa (pig) : DDX1 (DEAD-box helicase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38215,591,868 - 15,631,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37215,731,745 - 15,771,235 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36215,649,221 - 15,688,676 (+)NCBINCBI36hg18NCBI36
Build 34215,682,367 - 15,721,823NCBI
Celera215,649,490 - 15,688,945 (+)NCBI
Cytogenetic Map2p24.3NCBI
HuRef215,583,004 - 15,622,496 (+)NCBIHuRef
CHM1_1215,661,598 - 15,701,093 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DDX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737232
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.