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Gene: VAV1 (vav guanine nucleotide exchange factor 1) Homo sapiens
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Symbol: VAV1
Name: vav guanine nucleotide exchange factor 1
Description: Exhibits guanyl-nucleotide exchange factor activity and phosphotyrosine residue binding activity. Involved in regulation of GTPase activity and regulation of cell size. Predicted to localize to the cytosol and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: oncogene vav; proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav proto-oncogene
Orthologs:
Mus musculus (house mouse) : Vav1 (vav 1 oncogene)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vav1 (vav guanine nucleotide exchange factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vav1 (vav guanine nucleotide exchange factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : VAV1 (vav guanine nucleotide exchange factor 1)
Canis lupus familiaris (dog) : VAV1 (vav guanine nucleotide exchange factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vav1 (vav guanine nucleotide exchange factor 1)
Sus scrofa (pig) : VAV1 (vav guanine nucleotide exchange factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,772,708 - 6,857,366 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37196,772,679 - 6,857,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,723,722 - 6,808,371 (+)NCBINCBI36hg18NCBI36
Build 34196,723,721 - 6,808,371NCBI
Celera196,714,968 - 6,799,596 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef196,535,153 - 6,619,808 (+)NCBIHuRef
CHM1_1196,772,530 - 6,857,195 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on VAV1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737234
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.