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Gene: Arl3 (ADP-ribosylation factor-like 3) Mus musculus
Symbol: Arl3
Name: ADP-ribosylation factor-like 3
Description: Exhibits several functions, including GTPase activating protein binding activity; magnesium ion binding activity; and purine ribonucleoside binding activity. Involved in several processes, including Golgi to plasma membrane transport; intraciliary transport; and protein localization to ciliary membrane. Localizes to axoneme; ciliary basal body; and ciliary transition zone. Is expressed in central nervous system; hippocampus; retina inner nuclear layer; and retina outer nuclear layer. Used to study autosomal recessive polycystic kidney disease and retinitis pigmentosa 2. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa. Orthologous to human ARL3 (ADP ribosylation factor like GTPase 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADP-ribosylation factor-like protein 3; ADP-ribosylation-like 3
Homo sapiens (human) : ARL3 (ADP ribosylation factor like GTPase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arl3 (ADP ribosylation factor like GTPase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arl3 (ADP ribosylation factor like GTPase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ARL3 (ADP ribosylation factor like GTPase 3)
Canis lupus familiaris (dog) : ARL3 (ADP ribosylation factor like GTPase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arl3 (ADP ribosylation factor like GTPase 3)
Sus scrofa (pig) : ARL3 (ADP ribosylation factor like GTPase 3)
Heterocephalus glaber (naked mole-rat) : Arl3 (ADP ribosylation factor like GTPase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1946,531,096 - 46,573,198 (-)EnsemblGRCm38mm10GRCm38
GRCm381946,531,109 - 46,573,182 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371946,605,599 - 46,647,575 (-)NCBIGRCm37mm9NCBIm37
MGSCv361946,584,420 - 46,626,396 (-)NCBImm8
Celera1947,294,795 - 47,342,296 (-)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Arl3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737247
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.